Cyclobenzaprine is close to the cheapest thing a pharmacy sells. A 10 mg tablet costs a pharmacy $0.01695, which means the plastic vial and the printed label cost more than the medicine inside them. Medicare Part D covered 7.4 million cyclobenzaprine claims for 2.7 million people in 2024 at an average of $8.37 per claim.
Then there is the other cyclobenzaprine market, where the same molecule in an extended-release capsule averaged $3,027.15 per claim. This guide covers both, plus what happened to Flexeril. Every figure below was researched on September 4, 2026.
What Does Cyclobenzaprine Cost Without Insurance?
Acquisition costs come from the CMS National Average Drug Acquisition Cost survey. Every generic row and the Tonmya row are effective August 19, 2026. Amrix is the split vintage on this page: its 15 mg and 30 mg rows still carry a January 1, 2026 date, which is eight months older than everything else here. Cash prices come from Drugs.com and SingleCare, both read September 4, 2026. The middle column shows a representative example, not a computed average.
| Option | Low | Average | High |
|---|---|---|---|
| CMS NADAC acquisition cost, one generic tablet | $0.01695 (10 mg) | $0.02145 (5 mg) | $0.24024 (7.5 mg) |
| Cash price, 30 generic tablets | $5.14 (10 mg) | $9.68 (5 mg) | $32.74 (7.5 mg) |
| Cash price, 90 generic tablets | $5.93 (10 mg) | $12.30 (10 mg) | $13.44 (5 mg) |
| Discount card, 30 generic 10 mg tablets | $7.80 | $10.80 | $10.80 |
| Average retail, 30 generic 10 mg, no card | $55.48 | $55.48 | $55.48 |
| CMS NADAC acquisition cost, one generic ER capsule | $0.89263 (30 mg) | $1.21998 (15 mg) | $1.21998 (15 mg) |
| Cash price, 30 generic ER capsules | $144.44 | $144.44 | $144.44 |
| Discount card, 30 generic ER 15 mg capsules | $51.80 | $54.80 | $1,093.65 |
| CMS NADAC acquisition cost, one Amrix capsule | $66.23256 (15 mg) | $66.23256 (15 mg) | $66.56709 (30 mg) |
| Brand Amrix, 60 capsules | $4,079.02 | $4,079.02 | $4,079.02 |
| CMS NADAC acquisition cost, one Tonmya sublingual tablet | $29.61222 | $29.61222 | $29.61222 |
| Brand Tonmya, 30 sublingual tablets | $916.32 | $916.32 | $916.32 |
The cheap end is well corroborated. Drugs.com listed 30 of the 10 mg tablets between $5.14 and $9.30 and 90 between $5.93 and $12.30, while SingleCare’s card price for 30 was $10.80, or $7.80 after a one-time $3 signup credit. Federal Part D data lands in the same place, at $8.37 per claim in 2024.
The unhelped counter price is the unsettled figure. SingleCare states an average retail price of $55.48 for 30 of the 10 mg tablets, but its own per-pharmacy rows on the same page ranged from $15.60 at Kroger to $36.90 at Albertsons the same day. Those chain rows move between reads and should be read as a picture of the spread, not as quotable prices. What is reliable is the shape: a $0.017 product can be sold to you for anywhere from $5 to $55 depending on nothing you control.
What Drives the Price
Immediate-release tablet versus extended-release capsule, which is the whole story. Generic ER capsules cost a pharmacy $0.89 to $1.22 apiece against $0.017 for the common IR tablet, and Drugs.com quoted $144.44 for 30 ER capsules against roughly $5 to $9 for 30 IR tablets. Medicare Part D paid $8.22 per ER dosage unit in 2024 against $0.142 per IR unit, and $351.49 per ER claim against $8.37. The molecule is identical; the release mechanism is what you are buying.
Brand Amrix is a separate market with almost nobody in it. Two independent sources agree on the number: CMS prices an Amrix capsule at $66.23 to $66.57 and Drugs.com lists $4,079.02 for 60. Part D data shows why it stays high. Amrix claims fell from 657 in 2020 to 148 in 2024, and over exactly that period the average spending per dosage unit rose from $41.84 to $55.64. Falling volume and rising price is the normal end-of-life pattern for a brand whose generic has taken the market.
Strength, but not the way you would expect. The 5 mg tablet costs a pharmacy slightly more than the 10 mg ($0.02145 against $0.01695), and the 7.5 mg costs 14 times the 10 mg at $0.24024. There is no dose logic there at all; it is purely a function of how many manufacturers make each strength. Retail follows the same curve, with 30 of the 7.5 mg at $32.74 against as little as $5.14 for 30 of the 10 mg.
Flexeril is gone, and that is a pricing fact rather than trivia. Drugs@FDA lists both Flexeril tablet strengths under NDA 017821 as discontinued, and the drug is absent from both CMS’s acquisition survey and 2024 Part D claims. Retail sites still print the name because prescribers and patients still use it. If a pharmacy quotes you a “brand” price for Flexeril, that is a data artifact, and the correct response is to ask for the generic price.
There is now a new brand in the category. Tonmya, a cyclobenzaprine sublingual tablet approved under NDA 219428 and held by Tonix, appears in the August 19, 2026 CMS file at $29.61 per tablet, and Drugs.com lists $916.32 for 30. It is a new product rather than a replacement for the tablet, and its published copay card is limited to commercially insured patients, which is exactly the population this site is not writing for.
Cash Price vs. Insurance
Cyclobenzaprine is the clearest case on this site of a cash price beating a copay. If your plan charges a $10 or $15 generic tier, a $5 to $9 cash price wins outright and never touches your pharmacy benefit. Even a card price of $10.80 ties most generic tiers.
The usual tradeoff applies, and on this drug it barely registers. Money spent outside the plan does not count toward your deductible or out-of-pocket maximum, and you cannot stack a discount card with insurance on the same fill. Our gabapentin cost guide reaches the same conclusion for the same reason, and our Seroquel and quetiapine cost guide shows the same $9-versus-$150 pattern in a different drug class.
The place insurance actually matters is the extended-release capsule, and specifically brand Amrix. At $4,079 for 60 capsules there is no published patient assistance program and no manufacturer coupon listed on Drugs.com, so a cash payer has no route to the brand at all. The generic ER capsule at about $144 for 30 is the realistic ceiling for a cash payer who needs the once-daily form.
Cyclobenzaprine is also frequently prescribed alongside physical therapy or chiropractic care rather than instead of it, and that is usually where the actual money goes. Our physical therapy cost guide and chiropractor cost guide cover those bills, which routinely run 20 to 100 times the prescription. If a quote for any of it looks wrong, run it through our fair price checker before you pay.
How to Pay Less
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Ask for the 10 mg tablet if your prescription allows it. This is the biggest lever available and it costs nothing to ask. The 10 mg is the cheapest strength at wholesale and at retail, the 5 mg costs slightly more per tablet, and the 7.5 mg costs three to six times as much per fill. Splitting or switching strengths is a prescriber decision, not a pharmacy one, but it is a fair question to raise.
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Run a free discount card before you fill. SingleCare’s cyclobenzaprine page, prices updated September 4, 2026, showed $10.80 for 30 of the 10 mg tablets, or $7.80 after a one-time $3 signup credit, against a $55.48 stated average retail price. Our comparison of GoodRx vs. SingleCare explains how to price the same prescription both ways and why the quote you see online can move between visits.
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Do not count on the Walmart $4 program for this one. Walmart’s drug list, effective March 24, 2025 and read September 4, 2026, does not include cyclobenzaprine at any strength or any tier. Tizanidine 2 mg and 4 mg sit in the $9 per 30 days and $24 per 90 days tier and methocarbamol 750 mg sits in the $15 and $38 tier, so if a program price matters to you, that is a conversation to have with the prescriber rather than the pharmacy.
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Fill 90 days at a time when the prescription is ongoing. Cyclobenzaprine is not a federally scheduled controlled substance, so 90-day fills and mail order are genuinely available. Drugs.com’s larger pack sizes drop the 10 mg tablet to as little as $0.04 apiece at 180 count against $0.31 at 30 count, and the 5 mg to $0.15 at 90 count against $0.32 at 30.
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Refuse the extended-release capsule if the tablet was an option. A generic ER capsule costs about 50 to 70 times what an immediate-release tablet costs, and the brand version costs roughly 3,900 times as much at wholesale. If a prescription arrives written for the ER capsule, ask what the plain tablet would cost before you pay for the capsule, and check the card price both ways. SingleCare’s own ER page quoted card prices from $54.80 to $1,093.65 for the identical 30-capsule fill, which is the widest single-page spread we have seen on any generic.
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Get the visit priced too. Cyclobenzaprine is almost always prescribed at an urgent care or primary care visit after an injury, and that visit is the real bill. A free or sliding-scale clinic can often handle it for a fraction of the cost, and if a clinic or hospital bill has already landed for more than you expected, our guide to negotiating medical bills covers what to do next.
Bottom Line
Budget $5 to $12 for 30 generic cyclobenzaprine tablets and treat anything above about $20 as a reason to run a discount card rather than a fact about the drug. The 10 mg is the cheap strength, the 7.5 mg costs three to six times as much per fill, and paying full retail with no card can cost $55 for a product that reaches the pharmacy at $0.51 for the same 30 tablets.
Flexeril is discontinued and is not a product you can buy, whatever a price page tells you. The expensive versions that do exist are the extended-release capsule at about $144 for 30 generic capsules, brand Amrix at $4,079 for 60, and the new sublingual Tonmya at $916 for 30. In every one of those cases the fix is a conversation with the prescriber about whether the plain tablet will do, not a different pharmacy.